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KMID : 0857020100250010098
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Kosin Medical Journal
2010 Volume.25 No. 1 p.98 ~ p.101
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Respiratory Arrest Caused by Inadvertent Intrathecal Injection of High Dose Morphine : A Case Report
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Sung Sang-Hoon
Yu Soo-Bong
Ryu Sie-Jeong
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Abstract
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Epidural or intrathecal morphine injection is a useful method for management of postoperative pain and cancer pain.
But the effect of intrathecal morphine is ten to twenty times more potent than epidural morphine. So inadvertent intrathecal injection of morphine during epidural injection can induce serious side effect. The authors report a patient who experienced respiratory arrest and loss of consciousness due to inadvertent intrathecal injection of high dose morphine during epidural injection for management of cancer pain. The patient was treated with intravenous bolus and infusion of naloxone for 8 hours and assisted ventilation with Ambu and she was recovered completely without any sequela.
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KEYWORD
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intrathecal injection, morphine, naloxone, respiratory arrest
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